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PNC-27 5mg

Price range: €77.84 through €449.98

Parameter Specification
Product Name PNC-27
Sequence H-Pro-Pro-Lys-Lys-Lys-Arg-Lys-Val-Glu-Leu-Asp-Ala-Val-Ala-Ser-His-Leu-Gly-Met-Glu-Cys-Met-OH
Molecular Formula C123H202N34O33S2
Molecular Weight 2729.2 g/mol
CAS Number 1373124-00-5
Purity Grade ≥98% (HPLC)
Physical Form Lyophilized White Powder
Standard Dosage Unit 5mg per vial
Storage Conditions Store at -20°C (Lyophilized); 2°C to 8°C (Reconstituted)
Primary Application Laboratory Research & Biochemical Analysis
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Description

PNC-27 5mg is a synthetic membrane-active peptide designed specifically for biochemical evaluation and cellular research applications. Researchers looking to buy PNC-27 5mg Germany and across the broader European market rely on verified high-purity compounds to maintain accuracy in laboratory settings. Every batch available through Peptide Lab Europe undergoes strict quality verification to ensure consistent structural integrity and analytical reproducibility.

What is PNC-27 5mg?

PNC-27 is a specialized research peptide composed of a 28-amino acid sequence derived from the HDM-2 binding domain of the p53 tumor suppressor protein, combined with a transmembrane-penetrating leader sequence. This unique biochemical structure enables the peptide to interact specifically with target cellular membranes.

Manufactured using advanced Solid-Phase Peptide Synthesis (SPPS), each 5mg vial provides precise quantitative potential for high-level molecular research. The final product is lyophilized to preserve molecular stability during storage and transit.

Mechanism of Action

The core mechanism of PNC-27 revolves around its affinity for HDM-2 proteins present within cell membranes. Upon binding, the peptide alters membrane stability, inducing pore formation that leads to selective cell lysis in specific non-normal cell lines.

Because the structural target is localized primarily to damaged or transformed cells, healthy non-transformed cells remain unaffected in experimental models. This selective membrane-disrupting property makes PNC-27 a critical molecule in ongoing oncology and membrane-dynamics research.

Biochemical Benefits and Research Applications

  • Targeted Membrane Studies: Provides researchers with a reliable model for studying selective cellular pore formation.

  • p53 Pathway Research: Facilitates deeper investigation into HDM-2 binding interactions and cell regulatory mechanisms.

  • High Reproducibility: Lyophilized at ≥98% purity to eliminate experimental variables and baseline noise.

  • Cellular Lysis Kinetics: Helps researchers map localized pore formation without damaging healthy cell controls.

Reconstitution, Stability, and Handling

To preserve peptide stability, store the un-reconstituted vial in a freezer at -20°C away from light exposure. Before experimental use, reconstitute the powder using Bacteriostatic Water or Sterile Reagents, allowing the solution to dissolve naturally without harsh agitation.

Once mixed, maintain the solution between 2°C and 8°C and use within the recommended laboratory protocol timeframe. Avoid repeated freeze-thaw cycles, as temperature fluctuations degrade delicate peptide chains.

Safety and Product Longevity

PNC-27 5mg is synthesized exclusively for in vitro research and laboratory experimentation. It is not intended for diagnostic, therapeutic, or human consumption.

Proper storage keeps the lyophilized powder stable for up to 24 months from the manufacturing date. When ordering from Peptide Lab Europe, batches ship in protective cold-chain packaging to ensure thermal integrity upon arrival.

Ordering and European Shipping

When you choose to buy PNC-27 5mg Germany or order across international territories, rapid delivery and product authenticity are paramount. Our logistics infrastructure ensures fast, discreet shipping with full tracking capabilities.

We prioritize strict analytical standards, batch transparency, and dedicated customer support to support your laboratory’s ongoing research demands. Secure your supply today to maintain continuous progress in your experimental studies.

Additional information

Quantity

1 Pack, 5 Packs, 10 Packs